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Rep. Patrick J. Kennedy Tuesday plans to visit the Alexion Pharmaceuticals plant in Smithfield, where the company says he will speak about the historic spike in federal grants for medical research included in the federal stimulus bill. The hour-long visit begins at 9:30 a.m. Kennedy visited the plant a year ago. But this time, a lull in manufacturing will allow the congressman to tour the full complex without slipping on a protective hat, boots, gloves and safety glasses, a procedure that takes 30 minutes. Alexion, one of only two major biomanufacturing businesses in Rhode Island, is among the state's most closely watched new companies. Headquartered in Cheshire, Conn., Alexion bought the former Dow Chemical plant in 2006. Two years later, it completed a massive renovation to prepare the plant to produce Soliris, the only drug approved to treat paroxysmal nocturnal hemoglobinuria, a rare disease that destroys red blood cells and can lead to severe anemia, blood clots and kidney and liver damage. The U.S. Food and Drug Administration approved the drug in March 2007, a milestone most startups never see. The company was founded in 1992. But two years after it began selling Soliris in the U.S, Alexion still relies on a contract manufacturer, Lonza Biologics, to produce the drug. That could soon change, with a final FDA inspection scheduled for later this year, Alexion spokesman Irving Adler told The Providence Journal on Monday. If all goes well, Alexion hopes to begin selling Soliris produced in Smithfield by next year, Adler said. "Patients all over the world are depending on this drug produced in Rhode Island," he said. Alexion has invested $116 million in the Smithfield plant, including the salaries paid to its 100 workers, mostly scientists and technicians. In all, Alexion has 500 employees. The company has also used the Rhode Island complex to produce Soliris for clinical trials testing other uses of the drug. This year, it plans to organize eight clinical trials involving five diseases. In its first full year of sales, Soliris generated $259 million for Alexion, the company reported in its full-year results. (Read Alexion's annual report here.) The company recorded $33.1 million in net income for the year, compared to a loss of $92.3 million in 2007. For more breaking business news, read the Projo Biz Blog. |
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